ChCl–Malic Acid DES
Preparation
ChCl–Malic Acid DES
Step 1.
Add to a 500ml round-bottomed flask.
Choline Chloride
13.35
g
Step 2.
Add on top of ChCl in flask
L-Malic Acid
12.81
g
Step 3.
Insert thermometer and magnetic stir bar into flask and place the flask in electric mantel heater
Step 4.
Turn heater/stirer on and monitor heat. You want to maintain the temperature between 70–75°C.
Step 5.
As the sample heats up, monitor phase transition: grainy (5 min) → pasty (15 min) → liquid (40–60 min). As the mixture transitions to liquid phase, periodically hold flask to light; inspect for particles. If clear → proceed; if cloudy → heat 10 min more.
Step 6.
Turn off the heater. Turn down the stirring speed and continue stirring while cooling to room temp (~25°C)